Sum Frequency Generation Studies on Bioadhesion: Elucidating the Molecular Structure of Proteins at Interfaces
نویسندگان
چکیده
منابع مشابه
Broad-Bandwidth Chiral Sum Frequency Generation Spectroscopy for Probing the Kinetics of Proteins at Interfaces
The kinetics of proteins at interfaces plays an important role in biological functions and inspires solutions to fundamental problems in biomedical sciences and engineering. Nonetheless, due to the lack of surface-specific and structural-sensitive biophysical techniques, it still remains challenging to probe protein kinetics in situ and in real time without the use of spectroscopic labels at in...
متن کاملDetection of chiral sum frequency generation vibrational spectra of proteins and peptides at interfaces in situ.
In this work, we demonstrate the feasibility to collect off-electronic resonance chiral sum frequency generation (SFG) vibrational spectra from interfacial proteins and peptides at the solid/liquid interface in situ. It is difficult to directly detect a chiral SFG vibrational spectrum from interfacial fibrinogen molecules. By adopting an interference enhancement method, such a chiral SFG vibrat...
متن کاملChiral Vibrational Structures of Proteins at Interfaces Probed by Sum Frequency Generation Spectroscopy
We review the recent development of chiral sum frequency generation (SFG) spectroscopy and its applications to study chiral vibrational structures at interfaces. This review summarizes observations of chiral SFG signals from various molecular systems and describes the molecular origins of chiral SFG response. It focuses on the chiral vibrational structures of proteins and presents the chiral SF...
متن کاملToward a simple molecular understanding of sum frequency generation at air-water interfaces.
Second-order vibrational spectroscopies successfully isolate signals from interfaces, but they report on intermolecular structure in a complicated and indirect way. Here, we adapt a perspective on vibrational response developed for bulk spectroscopies to explore the microscopic fluctuations to which sum frequency generation (SFG), a popular surface-specific measurement, is most sensitive. We fo...
متن کاملInterfacial water structure at polymer gel/quartz interfaces investigated by sum frequency generation spectroscopy.
Interfacial structures of water at polyvinyl alcohol (PVA) and poly(2-acrylamido-2-methypropane) sulfonic acid sodium salt (PNaAMPS)/quartz interfaces were investigated by sum frequency generation (SFG) spectroscopy. Two broad peaks were observed in OH stretching region at 3200 and 3400 cm(-1), corresponding to the symmetric OH stretching of tetrahedrally coordinated, i.e., strongly hydrogen bo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Adhesion
سال: 2009
ISSN: 0021-8464,1545-5823
DOI: 10.1080/00218460902996374